Ideas that move the mission forward

Explore our thoughts on investment, innovation, and mission.

Shripriya Mahesh
Andrew Parker
Sara Eshelman
Nolan Shah
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Announcing Spero Ventures Fund II
Writing

Announcing Spero Ventures Fund II

by Shripriya Mahesh and Andrew Parker •

Continuing our efforts to support companies building a healthy, sustainable, and fulfilling future.

Opportunities in Tech-Bio
Writing

Opportunities in Tech-Bio

by Nolan Shah •

The technologies making it faster, better, and cheaper to get life-saving medicines to patients.

In A Post-AI World, Who Are You Building For?
Writing

In A Post-AI World, Who Are You Building For?

by Shripriya Mahesh •

Discover how the rise of AI agents will transform your everyday shopping, from toilet paper to toothpaste, and uncover the key transactions that will resist automation.

Exposomics
Writing

Exposomics

by Nolan Shah •

Science's next moonshot.

Scaling Specialty Care
Writing

Scaling Specialty Care

by Nolan Shah •

Hinge Health's IPO and how we think about tech-enabled services.

Beginner’s Mind
Writing

Beginner’s Mind

by Shripriya Mahesh •

Discover the challenges and rewards of starting over, from developing new skills to bridging the gap between taste and capability, as one navigates a major career transition.

It Never Gets Easier
Writing

It Never Gets Easier

by Shripriya Mahesh •

Discover the surprising truth behind the startup founder's pursuit of the 'next level' – how achieving major milestones often fails to deliver the transformative impact imagined, as we quickly adjust to the new normal.