Ideas that move the mission forward

Explore our thoughts on investment, innovation, and mission.

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Sara Eshelman

Nolan Shah

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Spero Investment Thesis

by Nolan Shah , Sara Eshelman , Andrew Parker , Shripriya Mahesh , Marc Tarpenning and Stephen Wemple • May 12, 2026

Celebrating low-cost hardware in our portfolio.

Spero Investment Thesis

by Sara Eshelman , Nolan Shah , Andrew Parker , Shripriya Mahesh , Marc Tarpenning and Stephen Wemple • May 5, 2026

Complexities of low-cost hardware.

Spero Investment Thesis

by Sara Eshelman , Nolan Shah , Stephen Wemple , Andrew Parker , Shripriya Mahesh and Marc Tarpenning • Apr 28, 2026

Spero Investment Thesis

by Nolan Shah and Andrew Parker • Jan 8, 2026

Leading Canopy's $8M Series A.

Writing

by Nolan Shah • Nov 3, 2025

The technologies making it faster, better, and cheaper to get life-saving medicines to patients.

Spero Investment Thesis

by Sara Eshelman and Nolan Shah • May 19, 2025

Leading Persist's Series A.

Writing

by Nolan Shah • Apr 3, 2025

Science's next moonshot.

Writing

by Nolan Shah • Mar 27, 2025

Hinge Health's IPO and how we think about tech-enabled services.

Spero Investment Thesis

by Sara Eshelman • Oct 30, 2024

Co-leading Aralez Bio's $12M Series A.

Writing

by Nolan Shah • Jun 12, 2024

City design as the key to unlocking better health.